Compreendendo o Impacto do Gene APOE4 no Alzheimer

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Novos estudos sugerem que o APOE4 vai além de um fator de risco, sendo uma causa do Alzheimer.

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Novos estudos sugerem que o APOE4 vai além de um fator de risco, sendo uma causa do Alzheimer.

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Análise de 3.300 cérebros mostra 95% com duas cópias do APOE4 apresentam sinais de Alzheimer.

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Dados médicos de mais de 10 mil pessoas indicam relação entre APOE4 e níveis anormais de beta-amilóide.

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Beta-amilóide, proteína ligada ao Alzheimer, se acumula em quase todos com duas cópias do APOE4.

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Descoberta sugere que monitoramento de homozigotos APOE4 pode levar a intervenções preventivas eficazes.

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Novas informações podem ajudar no desenvolvimento de tratamentos personalizados para Alzheimer.

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Criação: ISABEL SANTOS

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